I did it once, about twelve years ago, just to prove to myself that I could.
It was kind of fun, but I have absolutely no desire to do it again. I tried running it as my "full time" distro but what I ended up with was something extremely fragile and decidedly not fun for me to use.
Nowadays I run a NixOS Minimal install, which is about the level of operating system that I like to work in.
