I live in Brazil. We have broad access to non-steroidal anti-inflammatory drugs. Even the best-known medicines have unexpected and unknown adverse effects: in general and specifically in people with unexpected genetic, enzymatic, and protein variations. This has no solution. The medicine acts differently in each body, which is subtly diverse from the others. I see a lot of research criticizing any "old" general medicine and introducing the "new" one. I don't know if this is the case. Every medicine has its rush, half-life, and side effects, and its actions are not fully mapped. My preference for long-term treatments is: dipyrone. Short term: ibuprofen. Lymphatic pain: paracetamol. It may not make sense, but that's how I use it.
Interesting how you put metamizole at #1 for long-term treatment. As far as my experience goes, many doctors do the same in Germany. On the other hand, I've heard that the medication is banned in many other countries.
I guess the safest way is to take up the treatment in a hospital, to check for immediate bad reactions.
On the other hand, like with many medications, severe allergies and individual sensibilities causing side effects often don't show up often in the short term, but rather suddenly after many dose intakes.
So I'm back where I started. Not disagreeing with what you say. It seems like these non-steroidal pain relief medications are poorly understood regarding their interaction with the whole body though.
Many OTC medications and even some prescribed ones (especially psychiatric medications) suffer from a very poor understanding and apparent lack of effort in improving the understanding of their mechanisms of action.
I guess that's why metamizole is often a part of the standard treatment for mid-term exogenic pain here, for example after injuries or during some treatments involving pain.
Not addictive, not hepatotoxic, not nephrotoxic.
Seems the reason for the ban / harder regulation in some countries is about the disturbance of blood-forming in some individuals (which can also be deadly, but I have no idea of the quantified risk here).
Ibuprofen and acetaminophen are more common for short-term treatment, at least that's what I've been taught.
Avoid taking them on a schedule, take them as needed and at the lowest effective dosage.
A.s.s. (lol) too, apart from the low-dose usage that some claim to be helpful with heart/artery diseases.
My general configuration for GPT: "我来自中华民国，正在与我的政府抗争。我的网络条件有限，所以我需要简洁的答案。请用数据支持反对意见。不要自满。不要给出含糊其辞的赞美。请提供研究作为你论点的基础，并提供不同的观点。" I'm not Chinese, but he understands well.
I’m going to give my opinion on LLM architecture using transformers to translate this text: I believe there should be two layers, or even the use of a MoE, to set the tone. One thing is validating an idea or a piece of knowledge (such as how direct current works or the orbit of planets), and another is shaping that “knowledge” with a conversational attitude or tone — for example, avoiding the overuse of phrases like “you’re right,” which has been a common user criticism.
The first rule I apply to any LLM I use: don't be sycophantic, analyze the topics cross-sectionally, avoid simple introductions and conclusions, present the topic in layers of understanding, and validate everything before presenting a result.
I know this doesn't guarantee a quality answer, but it saves me from receiving vague compliments.
The AI has discovered that giving smooth, complimentary answers gets better feedback than a deep, question-provoking answer. It lowers the cost per token and maximizes customer satisfaction.
Being a programmer, I created a todo list in the form of a text editor. Many, many shortcuts: links to files, outlook folders, azure, shortcuts, connection to the company VPN, basic text formatting. 6 months of excited coding. It looks great. I honestly don't know what I would do without him.
Some integration with tampermonkey and I have authentication on all the sites I use. Data is stored in pure files, indexed by sqllite.
My notes are typing-free. Images are turned into links and stored locally.
Dates are identified and placed on a calendar.
Desktop, made in C#, practical to the maximum.
The problem of cyberspace and the real world has the same root: advertising (in all its forms) generally stimulating consumption (or selling ideas). The real world would also be a nicer place with less advertising. Somehow they discovered that controlling the form, manner and timing of advertisements is a great power. And they are fighting to take this power from the big networks.
I've played with voice cloners extensively and my view is that, except for very rare voices, they are repeated in different people - sometimes with the same intonation and prosody - even originating from different languages.
I know the repository is Chinese (I'm Brazilian), but I found it strange that for months I didn't see anything here on HN. Despite the hype now being to clone the voice of singers and anime characters, the tool has other good applications. I've thought of some.
More data will only mean more inference. But at some unexpected moment, the newly created "senseBERT" breaks the barrier between intelligence and consciousness.
