I interviewed at Sikorsky back in the day. Sort of wish I had pursued it, because the factory floor was amazing, but the manager reminded me of a guy from The Sopranos, and then I got into medical school. But that floor, man. Swashplates. Have you ever seen a swashplate, naked and alone on a pallet? Thin wall machining. I mean, goddamn, that was some sexy machine work. But they wanted me to run business analytics for government cost-accounting programs. Fuck. That. Also, medical school.
From the article:
"These pictures each contain an inky black disc of nothing. A black sun hangs with pendant menace and mystery.
But they’re neither objects nor stains, rather punch holes made by Roy Stryker, director of the FSA’s documentary photograph program, and his team of editors. The holes marked pictures as unfit for purpose."
My first job out of college was as a junior engineering officer on a ship. I had taken naval architecture and the daily draft report was part of my job. The fuel king had a spreadsheet where the engineering watch input all the tank levels overnight. I added a sheet that took that data and solved all the tank problems, bouncy, incline, etc, and printed the report. So instead of two hours of number crunching, or one of my enlisted guys doing what he did (which was basically copy forward and subtract an inch a day), the report was completely automated, with fore, aft, and center draft. With zero human effort.
Apparently the guy who took my job when I left had a nervous breakdown. I feel a little bad about that, but not really. He should have paid attention in class.
I believe socialism has a pretty specific definition: government ownership and control of the means of production. Which is easy to grasp for steel mills, power plants, and hospitals. A bit trickier in the creative economy and the gig economy.
I am aware of the definition and I don't dispute it. But consider for a moment why socialism wants the state to own all means of production.
The point is to directly control the effects of economically relevant actions and not leave it to an emergent dynamic that results from direct actions and agreements between individuals (i.e. the invisible hand).
Socialists think that it is in everyone's best interest if the government plans what work needs to be done, what resources to allocate and under what conditions the product should be made available to users, which directly contradicts the way in which open source software is produced.
In my view, the similarities between the DoD and socialism are lot greater than the similarities between open source and socialism. Any particular open source project can of course adopt a military style command and control structure, but not the open source model as a whole.
Unfortunately, some people are going to read this wrong. For example: I know some folks who have "second dinner" after 8 pm. Their children are definitively obese, and I can see them citing this study as a reason to keep eating "a meal called dinner" after 8 pm.
How do you propose to infect cells deep inside solid tumors?How do you target cells that have lost cell surface markers? Your example, p16, is used in many cells intermittently, or only in certain microenvironments . How do you deliver? IV, topical, tumor injection (if so, what about needle tract seeding)?